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Treatment of the human skin model with alpha arbutin reduced melanin content to a 40% level of the control, without causing cell death [63]

doi: 10.1016/j.bbi.2015.03.016 81 NikolovaVLSmithMRBHallLJCleareAJStoneJMYoungAH

However, HSPB1 exhibits substrate-specific activity, and different variants may differentially affect the folding of distinct clients, complicating interpretation

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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Matsuo K., Yabuki Y., Fukunaga K