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10 M retinoic acid was used as a positive control for maturation towards a differentiated neuronal phenotype, as shown previously ( 2.2 DPI synergizes with MitoQ in MNA NB cells To assess whether MitoQ and DPI act synergistically in reducing cell viability, we treated two MNA NB cell lines (IMR-5/75 and Be(2)-C) with various concentrations of DPI and MitoQ

Many factors are presumably involved (Boogard et al., 1989), including relative distribution of N -acetyltransferase and aminoacylases, cellular and mitochondrial uptake mechanisms, susceptibility to inactivation of cysteine S -conjugate -lyases and nearby enzymes/macromolecules, relative K m values, competition from natural amino acid substrates, absolute level of the enzyme, the presence of the enzyme in mitochondria, and the presence of -keto substrate to keep the enzyme enzymatically active (if the lyase in question is an aminotransferase)

10.1007/s00586-006-0171-3 Eur

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This fatty shell acts as a protective shield, allowing the glutathione to pass through the digestive system intact

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