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This fact may explain the limited response effects observed

Berginer VM, Berginer J, Salen G, Shefer S, Zimmerman RD

47,49 Likewise, several reports have also suggested that p21 Cip1/WAF1 exerts a pro-apoptotic function under certain cellular stresses upregulating the pro-apoptotic protein Bax, activating the tumor necrosis factor family of death receptors and regulating components of the DNA repair machinery
Conditions such as lupus, Guillain-Barre syndrome, rheumatoid arthritis, and Sjorgens syndrome can also result in nerve damage

T cell metabolism serves as a network that connects T cells and neighboring cells during complex immune responses in both normal and diseased settings

Archives of Biochemistry and Biophysics , 464 ( 2 ), 241250
