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Combining EGCG and a therapeutic gene in a multifunctional nanocarrier significantly increased spatial learning and memory capacities in APP/PS1 and wild-type mice, suggesting that co-delivering these molecules may be highly effective in AD treatment [47]

ACh can regulate the effect of AMPK on mitochondrial cristae remodeling by stimulating the muscarinic ACh receptor, thereby alleviating the hypertrophy of cardiomyocytes induced by palmitic acid (40)

At this point, in the absence of carbohydrate intake, gluconeogenesis becomes critical

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In the four-component Ugi reaction, the five different isocyanide derivatives of 4-hydroxythalidomide, in the presence of tritylamine or methylamine, formaldehyde, and acid-containing derivative of the target ligand (JQ1 derivative) yielded different anti-BRD4 PROTACs 178