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Animal studies involved naturally aged male C57BL/6 mice that were 20 months old and younger controls that were 3 and 13 months old
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J Neuroendocrinol (2000) 12:31122

This inhibition promotes the breakdown of stored fat and prevents excessive fat storage, making it a promising candidate for weight management and metabolic health
Furthermore, VEGF may also increase the permeability of blood vessels, which might enable the extravasation of plasma proteins and contribute to the formation of a primitive vascular scaffold, thereby potentially promoting the process of angiogenesis

10.1016/j.mad.2019.111197 296 VirkM
