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By targeting NNMT and supporting NAD+ levels, it addresses cellular energy metabolism rather than manipulating appetite or stimulating the nervous system

In asymptomatic patients with risk factors (see Table 1: Patient Risk Factors Associated with B 12 Deficiency below) consider supplementation in lieu of testing

Conclusion: Optimizing Your B12 Therapy Optimizing B12 therapy means looking at the patients health, treatment goals, and how they react to treatment

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Elevated NAD Levels: Fuels mitochondrial function, DNA repair, and cellular resilience (Kannt & Pfenninger, Frontiers in Physiology )

A family of histone deacetylases known as sirtuins (Sirt 1-7) controls a number of proteins involved in cellular metabolism, stress responses, circadian rhythms, and endocrine functions