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doi: 10.1007/s11738-013-1483-7 163 SaijoY.LooE

The physiological role of vitamin E as a potent natural inhibitor of ferroptosis is also highlighted by the fact that sustained vitamin E deficiency or mutations in the TTPA gene, encoding for -tocopherol transfer protein, lead to neurodegeneration [153,154]

This indicates that the initial processes of BBB formation are not regulated by astrocytes[21]

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