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The study was carried out through various computational methods using Autodock Vina for docking of the protein and ligand and Desmond for MD simulation

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By a series of in vitro and in vivo studies, we demonstrated that STAG2 knockdown virtually had no effect on malignant phenotypes of BRAF-mutant thyroid cancer cells such as cell proliferation, colony formation and tumorigenic ability in nude mice compared with the control

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