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Lee YS, Lai DM, Huang HJ, et al

10.4103/1673-5374.320993 198 ZengT.LiJ.XieL.DongZ.ChenQ.HuangS.et al (2023)

In addition, UA232 activates the PERK/ATF4/CHOP pathway, triggers endoplasmic reticulum stress-associated apoptosis, and promotes lysosome-dependent cell death by increasing lysosomal membrane permeability, thereby effectively inhibiting the proliferation of breast cancer (MCF-7) and cervical cancer (HeLa) cells [1075]

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The PAH monomeric protein is composed of three functional domains
