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This damage may be related to oxidative damage or consumption of GSH during metabolism

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More significantly, MOTS-c administration shifted the trajectory of age-related metabolic decline, indicating that the peptide's benefits are not limited to preventing dysfunction in young animals but can partially reverse established decline [2]

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Chest 162 , 782791 (2022)

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Under HF conditions, ROS cleaved the TK bonds, exposing TPP targeting ligands and enhancing micelle accumulation in damaged cardiomyocytes (205)

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