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10.3390/ijms25052952 61 LindermayrC.YildirimA

Jo Y, Shim JA, Jeong JW et al (2024) Targeting ROS-sensing Nrf2 potentiates anti-tumor immunity of intratumoral CD8 + T and CAR-T cells [J]

Lack of oxygen (hypoxia) is a common feature of solid tumors, associated with tumor progression and resistance to chemo- and radiation therapies [2,3,4,5]

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Of these genes identified, down-regulated factors included the immune factors CXCL1, CXCL2, and CXCL5, the macrophage inflammatory protein CCL20, and the pattern-recognition associated protein DMBT1 (42)

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