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ber drei pharmakologische Hauptmechanismen VEGF-Aktivierung mit Angiogenese-Frderung (Neubildung von Blutgefen in geschdigtem Gewebe), Stickstoffmonoxid-Signalweg-Aktivierung fr Mikrozirkulation und anti-entzndliche Wirkung, sowie Wachstumsfaktor-Modulation (EGR-1, FAK) fr Zell-Migration und Geweberegeneration

In the 3xTg genetic mouse model, which contains three well established mutations for the development of AD, a chronic treatment for 90 days with ultramicronized PEA resulted in the rescue of the memory deficits typically observed in this phenotype of mice (Scuderi et al., 2018)

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Immune checkpoint inhibitor (Anti-PD-1 antibody) is trapped in the interior of the porous ZGO@TiO2 with paclitaxel (PTX) loaded liposome encapsulation to form ZGO@TiO2@ALP

10.1002/1873-3468.12590 FEBS Lett

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