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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Puglia C., Offerta A., Saija A., Trombetta D., Venera C

doi: 10.1139/h11-120 158 McAnultyLSCollierSRLandramMJWhittakerDSIsaacsSEKlemkaJMet al

2013 meta-analysis: A meta-analysis of 13 clinical trials including 3,629 adults with acute myocardial infarction who took L-carnitine (from 2.7 g/day for 5 days to 6 g/day for 12 months) versus placebo found that L-carnitine significantly reduced rates of all-cause mortality, ventricular arrhythmias, and new-onset angina

Furthermore, in another clinical trial study, Liang et al

One of them is via a change in monoaminergic signaling (mainly synthesis of the neurotransmitters dopamine and serotonin, which are important elements in motivation, reward pathways and arousal)