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3a, c), while the presence of DI lowered in a time-dependent manner the detectable amount of GSH within 4 h by 31% (1 mM DI) and by 88% (10 mM DI) (Fig

doi: 10.3389/fmed.2026.1813015 Received 17 February 2026 Revised 25 March 2026 Accepted 31 March 2026 Published 13 April 2026 Volume 13 - 2026 Edited by Raji Rajesh Lenin, SRM Institute of Science and Technology, India Reviewed by Neetu Kushwah, Boston Childrens Hospital and Harvard Medical School, United States Roco Salceda, National Autonomous University of Mexico, Mexico Updates Copyright 2026 Reiter, Sharma, Blasiak, Rosales-Corral and Loh

PMID: 38383406 Cell Death Discov Pregnane X receptor protects against age-related bone loss in males via PI3K/Akt-mediated inhibition of apoptosis

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Ddit3 , Bgn , Tmem150a , Sqstm1 , Hist1h2bc , Ccnd2 , Mxd4 , Ypel3 , Kdm5b , Mxra8 , and Grina , which were previously identified and preliminarily validated by single-cell sequencing, all exhibit increased expression with the replicative senescence of MEF cells and can serve as potential aging biomarkers for further investigation