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For example, 2-propyl-2-pentenoic acid (2-en-VPA), a byproduct of -oxidation, and 2-propyl-4-pentenoic acid (4-en-VPA), a byproduct of -oxidation, have been incriminated in the development of cerebral oedema and in the hepatotoxicity of VPA, respectively [1724]

Integrative computational approach identifies drug targets in CD4 + T-cell-mediated immune disorders

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The metabolic profile of intrahepatic cholestasis of pregnancy is associated with impaired glucose tolerance, dyslipidemia, and increased fetal growth

doi: 10.1038/s41580-018-0092-0, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 15.Ahmed NY, Knowles R, Dehorter N
