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Description

De novo design of four-helix bundle metalloproteins: one scaffold, diverse reactivities

Podocyte injury caused by Indoxyl sulfate, a uremic toxin and aryl-hydrocarbon receptor ligand

Author contributions MI: Methodology, Conceptualization, Data curation, Formal analysis, Writing original draft

Applying our workflow to a stroke model allowed us to not only map metabolic remodelling of the infarct and peri-infarct area over time, but also discover hitherto unnoted remote metabolic remodelling in the histologically unaffected ipsilateral sensorimotor cortex

K7M2-Luciferase (K7M2-Luc) cells are cancer cells that express the reporter gene luciferase, which reacts with its substrate (luciferin) to generate chemiluminescence