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Numerous studies have demonstrated that in T2DM patients, plasma GPX4 levels are reduced, whereas ACSL4, MDH, 4-HNE, and ROS levels are significantly elevated, indicating a strong link between oxidative stress in DM and ferroptosis [59,60,61,62]

[DOI] [PubMed] [Google Scholar] 162.Waring W.S., Goudsmit J., Marwick J., Webb D.J., Maxwell S.R

Hasegawa, and S

Hydroxyl radicals, among the most destructive ROS, can inflict severe oxidative damage on DNA, proteins, and lipids within sperm cells

The noise was digitally generated using RPvdsEx software 5.4 running on an RP2.1 Enhanced Real-time Processor (Tucker-Davis Technologies, Inc., or TDT), amplified by a PLX-3402 Power Amplifier (QSC Audio Products Inc.), and delivered through a JBL 2446H driver coupled to a JBL 3860A Bi-Radial Horn (JBL, Harman International), both mounted in the chamber ceiling