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Transport of long-chain native fatty acids across lipid bilayer membranes indicates that transbilayer flip-flop is rate limiting

Sayed AM, Abdel-Fattah MM, Arab HH, Mohamed WR, Hassanein EHM (2022) Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: role of TLR4/NF-B and c-Fos/c-Jun pro-inflammatory pathways and PPAR-/SIRT1 cytoprotective signals

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Specifically, patients exhibiting symptoms of peritoneal inflammation and abdominal infections, along with lactate concentrations exceeding 2 mmol/Lespecially when clinical suspicion focuses on peritonitis and small bowel compromise leading to necrosisare strongly advised to undergo surgical exploration[123]

However, one of the products, called NAPQI, is toxic to the body
