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Carnitine can also exert anti-inflammatory effects by inhibiting the polarization of M1 macrophages and reducing the activity of Th17 cells and other proinflammatory cell populations [50, 51]

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ULK1 can activate autophagy by phosphorylating Beclin-1 indirectly involved in the formation of VPS34-Beclin-1-ATG14 (69, 70)

Calvani, M., and E

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Standard treatment for EPSM horses is using high levels of fat in the diet, however, this can be harmful over a period of time as high-fat diets in horses have been shown to increase the chance of the development of insulin resistance and laminitis