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This reveals a context-dependent vulnerabilityof Tregs that could be exploited therapeutically, though balancing efficacy and immune related adverse events remains a challenge [118]

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Contraindications: Tropicamide (like atropine) is contraindicated in patients with because it can increase intraocular pressure due to relaxation of the ciliary muscle with subsequent obstruction of the canal of Schlemm

Furthermore, some cancer cells can develop resistance to oxidative stress, making antioxidant therapy less effective
