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Many small-molecule compounds with potent ferroptosis-inducing activity suffer from poor in vivo stability, rapid metabolism, low tumor tissue accumulation efficiency, and systemic toxicity, which limit their clinical application (125, 184)

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La science des formulations : pourquoi elles sont si diffrentes Comprendre la diffrence entre le rouge lvres et le baume lvres au niveau de la formulation permet d'expliquer pourquoi leurs performances sont si diffrentes sur vos lvres

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Cys 290 in the active center is poised to nucleophilically attack the MSA substrate which results in the formation of a covalent hemithioacetal

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