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GDH also plays an important regulatory role in the stimulation of insulin secretion by amino acids (especially leucine)

Autophagic degradation of ferritin in cytoplasm or lysosome, known as ferritinophagy, could lead to elevated intracellular iron levels, thereby accumulating ROS and eventually triggering ferroptotic cell death (Hou et al., 2016)

[DOI] [PMC free article] [PubMed] [Google Scholar] 165.Margetts PJ, Bonniaud P, Liu L, Hoff CM, Holmes CJ, West-Mays JA, Kelly MM

New York, NY: 2017

Pharmacokinetic and Pharmacodynamic Profiles of Orally, Duodenally and Subcutaneously Delivered Insulin in Beagle Canines

Insulin-like growth factor-I prevents apoptosis in sympathetic neurons exposed to high glucose