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Thus, targeting glutamine metabolism not only inhibits glutamine-dependent pathways, but also leads to a marked decrease in p-STAT1 and p-STAT3dependent IDO expression resulting in a robust reversal of the kynurenine/tryptophan ratio

A phase II clinical trial evaluated the efficacy of cabozantinib compared with traditional chemotherapy in the treatment of uveal melanoma (Xu et al., 2020)

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This association has contributed significantly to its popularity within cosmetic science and regenerative biology

[DOI] [PubMed] [Google Scholar] Srkzy M, Kovcs ZZA, Kovcs MG, Gspr R, Szcs G, Dux L

N.Munoz-OlivasR.Luque-GarciaJ