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The natural alkaloid piperlongumine significantly enhances tumor cell sensitivity to NK cellmediated killing by inducing ROS accumulation within tumor cells, disrupting protein homeostasis, and enhancing NK cell binding to tumor cells

[6] Peng H, Wang J, Chen J, Peng Y, Wang X, Chen Y, Kaplan DL, Wang Q

Peer review Peer review information Nature Reviews Drug Discovery thanks Michael Nauck, Stefan Trapp and the other, anonymous, reviewer(s) for their contribution to the peer review of this work
Conducted clinical studies have highlighted an often overlooked yet essential role of glutathione, which is digestive health

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"Acetaminophen and the cyclooxygenase-3 puzzle: sorting out facts, fictions, and uncertainties"
