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Complement activation, detected by the presence of C4d in the lungs of the two fatal cases, suggested that antibodyF protein immune complexes led to more severe disease 28

Int J Mol Sci 21: 1505, 2020

thus, iron deficiency results in decreased haemoglobin synthesis and a reduced capacity for oxygen transport, ultimately leading to iron deficiency anaemia (IDA)

The high amount of formate in the culture system is a stress factor for the bacterial growth 43 , and the bacteria need to remove this intermediate product during the metabolism of oxalate to prevent formate accumulation in the culture system

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Among a number of innovative immunomodulatory factors, lauric acid (LA) a saturated, medium-chain fatty acid, naturally found in high concentrations in oils (coconut, palm, black soldier fly larvae) exhibits strong antibacterial and antiviral properties, is particularly effective against gram-positive bacteria , inhibits biofilm formation, membrane biosynthesis and virulence factors, may eliminate vegetative cells and spores, and improves antioxidative capacity