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[DOI] [PubMed] [Google Scholar] 133.Hurt E.M., Thomas S.B., Peng B., Farrar W.L

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51, 74, 75, 76, 77, 78 The molecular mechanisms that underlie the cytotoxic potential of cytoplasmic CDDP are poorly understood, yet may involve: (i) the accumulation of reactive oxygen species (ROS) and nitric oxide (NO), which not only exacerbate CDDP genotoxicity but also exert direct cytotoxic effects by favoring the opening of the so-called permeability transition pore complex (PTPC)

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10.1186/s10020-024-00873-0 294 LuL.LiW.SunC.KangS.LiJ.LuoX.et al