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It has been demonstrated that endonuclease inhibition decreases cell lethality (69), suggesting that DNA fragmentation has a permissive role in APAP liver toxicity
10.1016/j.cbi.2014.08.013 141 NajimA.-A.CarolineA.AurlieB.SandrineD.JeanPaulC.NathalieL.et al (2004)

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Oxidative and nitrosative stress and immune-inflammatory pathways in patients with myalgic encephalomyelitis (ME)/chronic fatigue syndrome (CFS)

this is a novel ferroptosis regulation pathway that parallels the GSH/system-Xc/GPX4 axis
