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To determine if two of the genes, glyoxalase 1 and glutathione reductase 1, have a causal role in the genesis of anxiety, we performed genetic manipulation using lentivirus-mediated gene transfer
These included upregulated VD-regulatory genes in the liver and glucose-metabolism genes in muscle, increased levels of 25(OH)VD, reduced lipid peroxidation, and lower levels of protein carbonyl and TNF in the blood [56]

10.1105/tpc.105.040303 Plant Cell 110 SilvaJ
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