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Description
Targeting GST therefore provides a mechanistically relevant way to evaluate whether microbes-derived metabolites can interfere with this detoxification system and potentially sensitise bacteria to existing antibiotics
The interpretation of these findings requires caution, and further studies are essential to determine its broader translation and long-term safety
Eligible interventions include small molecules (including repurposed drugs), ATMPs (with GMPvalidated manufacturing appropriate for Phase I/II), biologics/new biological entities, and repurposed biologics
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Respiratory Medicine
292 ZhangY.ChenC.JiangY.WangS.WuX.WangK
