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Bone Strengthening One of the most well-known benefits of Vitamin D3 is its role in calcium absorption, which is essential for bone health

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*Correspondence: Changgang Sun, [email protected] These authors have contributed equally to this work and share first authorship This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Cell and Developmental Biology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Together, they also support the longevity of fibroblasts through interaction with growth hormone, leading to improved tissue repair and regeneration

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Their complementary mechanisms one acting primarily through growth factor upregulation and GI-cytoprotection, the other through actin polymerization and systemic cell migration make them uniquely interesting both individually and as a combined research subject