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For bioinformatics analysis, data normalization was conducted using the Trimmed Mean of M -values method in edgeR, and pathway analyses were performed with Fishers exact test

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Choo YS (2004) Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release

Mirastschijski, U

Melanocyte stem cells deplete and no longer differentiate into as many melanocytes (leading to less hair pigmentation) Melanocytes become damaged and no longer produce as much melanin (leading to less hair pigmentation) Again, no one is sure why this might happen