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The fact that oxaliplatin is more efficient than cisplatin could be explained by the fact that DNA-oxaliplatin adducts are more effective in inhibiting DNA synthesis and less susceptible to the repair mechanisms of the cell (Dilruba and Kalayda, 2016
Balstad TR, Carlsen H, Myhrstad MCW, Kolberg M, Reiersen H, Gilen L, Ebihara K, Paur I, Blomhoff R
doi: 10.2217/fon.11.145
Whether cycling is necessary from a safety perspective remains unknown
Overload of NADPH oxidase causes decreased pollution defense to free radicals generated by pollution or pathogens
doi: 10.1073/pnas.2013595117
