glutathione cancer growth Study Finds Cells Use as Fuel to Drive Glutathione metabolism in cancer progression

Toppo S, Vanin S, Bosello V, Tosatto SC

The observed accumulation of GSH in Sp treated cells was probably due to reduced activity of -glutamyl transpeptidase (GGT), an enzyme responsible for glutathione catabolism 36

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Cell Death Dis (2026)

The increased oxidative and nitrosative stress generated by all these processes could be exploited by EBV-infected cells for their transformation through viral DNA methylation, preventing their replication and favoring the establishment of different types of latency that allow evasion of the immune system

Especially, Ca 2+ fluxes involving the ER and mitochondria govern apoptosis [96]