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This causes a problem for those on a Vegan diet as it makes it more difficult for them to obtain it through their diet

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Concerning the systemic physiological role of CRH, studies on CRFR1, CRFR2, and CRH deficient mice show that CRH has effects on the immune, gastrointestinal, reproductive and cardiovascular systems [16]

This difference relates to how the fragment may act at the cellular level

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