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Modern IV equipment with air-detection sensors has made this event extremely rare, and fully priming IV tubing before use is the main preventive step

The latter modification is consistent with our recent report that parkin thiols participate in redox chemistry to neutralize highly reactive molecules , e.g., H 2 O 2 and dopamine metabolites [53], as well as with the literature on transient S- glutathionylation of redox-sensitive proteins as a cytoprotective mechanism against rising concentrations of ROS [27]

Low-risk factors for G2G4 ALT elevation included higher FA levels before premedication [OR: 0.45, 95% CI: 0.250.83

Just like cyanocobalamin, it has to be reduced from state +3 to +1 before it can become either methyl B12 or adenosyl B12