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However, some may experience mild, temporary irritation, redness, or even minor breakoutsoften referred to as 'copper peptide uglies'especially when first starting or using higher concentrations

372,373,374,375 More recently, variants of the AAV have been investigated for its potential use for BBB penetration

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It was found that BV causes cell death by generating hydroxyl radicals (Gajski et al., 2024)

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This leads to whats called higher bioavailability, meaning a greater percentage of the dose reaches the target tissues
