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Together, these findings further substantiate the stress-associated anxiety-like phenotype in KI mice and demonstrate that, despite repeated elevated plus maze testing, a 7-day inter-test interval is sufficient to reliably detect anxiety-like behavior

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One example of this is tetrahydrobiopterin (BH4), an essential enzyme cofactor that is required to produce tyrosine and dopamine, that has been discussed as a potential treatment target (Sperner-Unterweger et al., 2014)
Sample size With an error probability of 0.05 and a statistical power of 80%, the largest sample size requirement was determined based on serum ALT concentrations as the dependent variable 16

However, the exact cause remains unclear

doi: 10.1177/1721727X1401200304
