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Importantly, such direct CNS delivery does not negate the role of the bonebrain axis, which provides an additional, complementary pathway by which SIN can modulate systemic immunity and bone-derived signaling, ultimately influencing cerebral ischemia outcomes

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Impaired autophagy response in human hepatocellular carcinoma

It helps in the production of myelin, a protective sheath that surrounds and insulates nerve fibers, allowing for efficient transmission of nerve signals

Longevity & senescence The main reason people seek FOXO4-DRI: studied as a senolytic to clear senescent 'zombie' cells in aged mice preclinical only, not approved

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