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Patients with AD often develop CHE after exposure to irritants or allergens, and isolated AHE can often overlap with or become primarily driven by ICD or ACD, complicating clinical diagnosis and treatment [4, 5]

Additionally, JAK3 and STAT5B mutations impair Foxp3 expression, disrupting regulatory T cell (Treg)-mediated immune tolerance
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Evidence Ledger: What Do We Actually Know

Oxidative stress and mitochondrial dysfunction in chronic kidney disease
Data from over 36 million delivery hospitalizations revealed that there was a significant increase in HC prevalence over the studied period
