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A meta-analysis of randomized controlled trials showed that use of antibiotics for acute rhinosinusitis offers a small therapeutic benefit over placebo, with a corresponding rise in the risk for adverse events.5 Reactive Oxygen Species (ROS) are produced under physiological conditions and their production and antioxidant activity are balanced

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In a mouse limb bud culture system, acrolein induced impairment of limb bud differentiation, indicative of a teratogenic action (Stahlmann et al., 1985)

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