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[DOI] [PMC free article] [PubMed] [Google Scholar] 349.Ying W

Biochem J 2012;441:763-787

SGLT2 is expressed nearly exclusively in the apical membranes of epithelial cells of the proximal tubule of the kidney and has been shown to be responsible for approximately 90% of the renal glucose reabsorption (see Figure below)

In Macaca fascicularis mPGES-2, the dimerization remains similar to the canonical assembly and occurs through an insertion of two -helices and two -strands (3443) between 3 and 4 that interacts with those of the other monomer (Figure 5E) (Yamada et al., 2005

The homologous DHAR and GST have similar functions involving their redox active sites and GSH binding site residues (Dixon et al., 2002

PMID: 31664451
