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Thyroid follicular epithelial cells use thyroid peroxidase (TPO) to activate the iodine that has been ingested

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(B) 8226/S, 8226/S-CR, 8226/S-ATOR05 cells were treated with 2 M ATO alone or in combination with either 100 M BSO or 10 mM NAC for 24 h and apoptosis was determined using flow cytometry

Ethical approval This article does not contain any studies with human participants or animals performed by any of the authors

These antioxidant drugs could be used for the treatment of various pathological diseases, and therefore gained importance in clinical as well as research areas

218 , 219 Therefore, mitochondria-targeted photodynamic therapy which generates mROS to induce cell death, and immunotherapy, which induces ICD, play a synergistic role in cancer treatment