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Pangrazzi L, Cerilli E, Balasco L, DallO GM, Chelini G, Pastore A, et al
Thus, activation of NFB by ROS (or other signaling pathways) upregulates the expression and activity of ROS generators, such as NADPH oxidase 1 and 2 (NOX1 and NOX2) that produce superoxide [9, 10]
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GSH was also shown to directly reduce Trx1 and Trx2, and the addition of Grx2 increased Trxs repair and enzyme activity [7, 55]
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