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tissue vitamin E and other antioxidants are, at best, contradictory.sup.(55) the tissue glutathione levels are more consistently reported to decline with old age in laboratory animals.sup.(56,57) and man.sup.(58-61)

The small intestine of the control, vehicle, and solvent groups showed normal histological structures of the intestinal layers and villi (Fig

Furthermore, IMP treatment reversed LPS-induced decreases in ALDH3A1, Nrf2, HO-1, and GPX4 protein levels (Fig