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The MCF-7 cells were seeded in 96-microwell plates at a density of 5 10 3 cells/well and incubated overnight at 37 C
The final step in the synthesis of glutathione is the linkage of the dipeptide gamma-glutamyl-cysteine with glycine by the action of glutathione synthetase
Cadmium in bone has a biological half-life of about 30 years
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During iron scarcity, the IRE-IRP system also downregulates proteins associated with iron usage [37], including the haem synthesis protein, 5-aminolevulinic acid synthase (ALAS)-2 [38], and the tricarboxylic acid (TCA) cycle enzyme, mitochondrial aconitase 2 (ACO2), which requires a [2Fe-2S] cluster for catalysis [39]
[DOI] [PMC free article] [PubMed] [Google Scholar] 26.Cornford AS, Barkan AL, Hinko A, Horowitz JF
