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Severe reactive astrocytes precipitate pathological hallmarks of Alzheimers disease via H2O2 production

Kudryavtsev IV, Garnyuk VV, Nadeev AD, Goncharov NV (2014) Hydrogen peroxide modulates expression of surface antigens by human umbilical vein endothelial cells in vitro

ALS is mostly diagnosed based on clinical signs, using the revised El Escorial criteria, which require signs of both upper motor neuron (e.g., spasticity, brisk reflexes) and lower motor neuron damage (e.g., muscle wasting, twitching) in multiple body regions (Brotman et al., 2025)

Allergy testing may be done to look for tolerance to gluten, dairy, sunscreens, and hair product ingredients

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