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10.1002/cbic.201900774

2.2 Increased Hcy levels and MetS Hyperhomocysteinemia (HHcy) stands as a well-established independent risk factor for cardiovascular and cerebrovascular diseases (Sreckovic et al., 2017)

Ng and Henikoff, 2003) identifies three SNPs that are likely to impair cobalamin biosynthesis enzymes in Lineage 5 isolates (CobM D53G, CobO Q202R, CobU H50R)

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Nave T cells rely primarily on oxidative phosphorylation to generate ATP, whereas activated T cells shift their metabolism toward aerobic glycolysis (Warburg effect) to meet the demands of growth, proliferation, and effector functions, such as IFN- production (136)

The information gathered could be valuable for gaining a deeper understanding of disease mechanisms and could serve as a basis for the development of potential therapeutic agents [11]