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These include vitamin B12 deficiency and malabsorption that is caused by the following medical conditions, according to the NIH [1]: Pernicious anemia Tropical sprue Pancreatic insufficiency Surgery in the gastrointestinal tract Certain medications Deficiency in the diet Side effects of B-12 injections Also, according to the NIH, vitamin B-12 injections have some potential side effects, including [1]: Diarrhea Itching Swelling Risk of allergic reaction and anaphylaxis Can Vitamins Aid in Weight Loss

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10 These detailed studies further highlight the complexity of the mucosal barrier properties and reveal that alterations in cytoskeletal proteins and TJ-integral and -associated proteins can affect mucosal permeability as well as epithelial cell homeostasis

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