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Altogether, these data support the hypothesis that G6PD-d drives ROS accumulation and may thereby amplify proinflammatory signaling or gene transcription in the absence of an acute stimulus 30

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Investigating mitochondrial redox state using NADH and NADPH autofluorescence

The profound, crushing exhaustion, the unpredictable and terrifying symptom flares, and the isolating cognitive fog are not just 'in your head' or a sign of deconditioningthey are the very real, measurable manifestations of a body locked in a severe state of cellular energy depletion and systemic oxidative stress

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