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Natural antioxidant enzymes are usually susceptible to changes in temperature, pH, and chemical environment, leading to a decrease in their activity or complete inactivation [180]

5 Conclusion After a thorough review and analysis of existing literature, we have drawn the following conclusion: Antioxidants play a pivotal role in preventing neuropsychiatric disorders by effectively scavenging free radicals and mitigating oxidative stress, thereby forming a protective barrier for brain neural tissue

It is particularly dependent on the activity of several enzymes but this activity can be inhibited rendering these enzymes inactive

, 57 numerous genes implicated in apoptosis may be aberrantly methylated in cancer

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We thank Marcos Frank and Christopher Davis for their helpful comments
